1Clinical Medical College of Jining Medical University黑丝, Jining Shandong
2Department of Cardiology, Jining No.1 People’s Hospital, Jining Shandong
3Cardiovascular Research Institute, Jining No.1 People’s Hospital, Jining Shandong
Received: Jul. 18th, 2020; accepted: Aug. 3rd, 2020; published: Aug. 10th, 2020
ABSTRACT
AIM: To evaluate the correlation between COVID-19 and heart injury through meta analysis, and to provide evidence-based basis for clinical practice. Methods: Wanfang, CNKI, Chinese biomedical literature database, PubMed, Embase, Cochrane Library, Medline database were searched by computer to retrieve studies related to COVID-19 infection and heart injury. The search time ranges from January 1, 2020 to April 20, 2020. Rev Man5.3 and STATA software were used to analyze the included studies. Results: A total of 29 studies were included, totaling 4466 patients. The results of the meta analysis showed that the critically ill patients had higher troponin than the non-critical patients (p = 0.03); the patients with myocardial injury were more serious and had higher mortality (p = 0.002; p = 0.0001